2018 - Volume 3 - Issue 1 Articles
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Research Article | ArticleJanuary 12, 2018 | Pages : 205 - 450Abstract Ebola virus disease (EVD), also known as Ebola hemorrhagic fever is a fatal disease which spread outrageously from the month of March, 2014 on West Africa. It is very dangerous disease and no proper medicine or vaccine available till date. Experiment.....
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Research Article | ArticleJanuary 29, 2018 | Pages : 205 - 450Abstract Five phenylpiperazine derivatives of 1,4-benzodioxan have been designed, and evaluated for antimicrobial activities. Docking simulations have been performed to position compounds into the Tyrosyl-tRNA synthetase active site to determine their probabl.....
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Review Article | ArticleMarch 29, 2018 | Pages : 205 - 450Abstract Found mainly at the telomeric, promoter, ribosomal RNA and regulatory regions in genome, G4 quadruplexes are guanine-rich region that cause DNA strands to get folded into planar quadruplex with the help of Hoogsten hydrogen bonds and stabilization by.....
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Short Communication | ArticleMay 12, 2018 | Pages : 205 - 450Abstract Within this study we have used a computational approach to predict the ADME-Tox profiles, thepharmacokinetics properties and the biological effects of the most used parabens: methylparaben (MP), ethylparaben (EP), propylparaben (PP) and butylparaben .....
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Review Article | ArticleMay 18, 2018 | Pages : 205 - 450Abstract In silico toxicology plays a vital role in the assessment of safety/toxicity of chemicals and the drug development process. In silico toxicology aims to complement existing toxicity tests to predict toxicity, prioritize chemicals, guide toxicity test.....